Let the road set the pace.
This history-rich byway meanders along the banks of the Ohio River, hugging its shoreline and offering almost continuous views of the river. The history of the Ohio is found both in rural landscapes and quaint river communities, covering periods from Native American habitation through western settlement, affecting transportation patterns and industrialization.
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Before you drive
Make it a satisfying day
Choose a realistic section, then allow time for viewpoints, a town stop and breaks. Scenic mileage rarely tells the whole story of how long an outing will take.
Match the road to your vehicle
Check the exact roads for your car, RV or motorcoach. Tunnel dimensions, turning space, grades and road surfaces can matter as much as distance.
Route overview and designation: Federal Highway Administration, America’s Byways. Research: October 2026. This is a travel idea, not live navigation or a guarantee that the full route is open. Confirm exact roads, current conditions, parking and any attraction reservations before departure.